Product Name	PAF
Chinese Name	血小板活化因子抗体
Alias	platelet-activating factor; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate; 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine; 1-hexadecyl-2-acetyl, PAF(C16.
Product Type	Small molecule anti
Research Area	Drugs and Compounds
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	0.524kDa
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated PAF
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Platelet-activating factor, a compound that reduces inflammation by increasing permeability of blood vessels and contracting various involuntary muscles such as those in airways. It is a phospholipid with a wide range of proinflammatory actions, is immediately degraded and inactivated in vivo by PAF acetylhydrolase. SWISS: N/A CAS: 74389-68-7 血小板活化因子（platelet-activating factor，PAF）是一种内源性具有生物活性的磷脂。由中性粒细胞、血小板、肥大细胞、endothelial cells和巨噬细胞产生。除早期发现它有强烈引起血小板聚集和脱颗粒作用外，近年来的研究发现它还具有广泛的生物活性，作为一种独特的cell factor参与体内多种生理、病理过程，包括激活中性粒细胞，使其聚集、趋化、释放氧自由基和白三烯，抑制T细胞增殖，刺激B细胞合成IgG和IgE，抑制心肌收缩力，增加血管通透性，引起体循环血压下降和肺动脉高压等。由于它具有广泛的高强度的生物活性，故PAF被认为是与过敏反应有关的关键性介质之一。
Product Picture	Tissue/cell: rat colon tissue;4% Paraformaldehyde-fixed and paraffin-embedded Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum) at 37℃ for 20 min Incubation: Anti-PAF Polyclonal Antibody, Unconjugated(SL1119R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining

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