Product Name	ADGRE1
Chinese Name	表皮生长因子样激素受体1（EMR1）抗体
Alias	F4/80; Adhesion G protein-coupled receptor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1; EGF like module receptor 1; EGF TM7; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone receptor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.
literatures	Specific References  (15)     |     SL11182R has been referenced in 15 publications. [IF=13.903] Tang Y et al. Overcoming the Reticuloendothelial System Barrier to Drug Delivery with a "Don't-Eat-Us" Strategy. ACS Nano. 2019 Nov 5.  IHF ;  Mouse.   PubMed:31689086 [IF=13.081] Xu Jun Yan. et al. Interleukin-5-induced eosinophil population improves cardiac function after myocardial infarction. CARDIOVASC RES. 2022 Jul;118(9):2165-2178  IF ;  Mouse.   PubMed:34259869 [IF=7.109] Xiong, Jingjie. et al. CircRNA mmu_circ_0000021 regulates microvascular function via the miR-143-3p/NPY axis and intracellular calcium following ischemia/reperfusion injury. CELL DEATH DISCOV. 2022 Jul;8(1):1-13  IHC ;  Mouse.   PubMed:35821018 [IF=6.208] Chao Huang. et al. Loss of TRIM67 Attenuates the Progress of Obesity-Induced Non-Alcoholic Fatty Liver Disease. INT J MOL SCI. 2022 Jan;23(13):7475  IHC ;  Mouse.   PubMed:35806477 [IF=5.162] Sun Y et al. Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization. Int J Biol Macromol . 2020 Oct 15;161:704-711.  WB&IHF-P ;  Mouse.   PubMed:32544579 [IF=4.225] Liu Yi. et al. Overexpression of Activating Transcription Factor 3 Alleviates Cardiac Microvascular Ischemia/Reperfusion Injury in Rats. Front Pharmacol. 2021 Feb;12:71  IF,IHC ;  Rat.   PubMed:10.3389/fphar.2021.598959 [IF=3.943] Quanyu Chen. et al. Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model. Int Immunopharmacol. 2021 Jan;90:107180  IHC ;  Hamster, Rat.   PubMed:33221167 [IF=3.388] Liu X et al. KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway. Cell Signal. 2019 Sep 9;64:109415.  ICF ;  Mouse.   PubMed:31513837 [IF=3.06] Li T et al. Withanolides, extracted from Datura metel L. inhibit keratinocyte proliferation and imiquimod- induced psoriasis-like dermatitis via the STAT3/P38/ERK1/2 pathway. Molecules. 2019 Jul 17;24(14). pii: E2596.  WB ;  Mouse.   PubMed:31319488 [IF=3.041] An G et al. Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages. Oncol Rep. 2019 Dec;42(6):2499-2511.  IHC-P ;  Human.   PubMed:31578575 [IF=3.04] Jiang X et al.Loss of MD1 exacerbates myocardial ischemia/reperfusion injury and susceptibility to ventricular arrhythmia.(2018)Eur J Pharmacol;844:79-86.  IHC ;  Mouse.   PubMed:30458167 [IF=2.939] Wei S et al.Overexpression of Toll-like receptor 4 enhances LPS-induced inflammatory response and inhibits Salmonella Typhimurium growth in ovine macrophages.(2018) Eur J Cell Biol.  ICF ;  sheep.   PubMed:30522781 [IF=2.939] Yang R et al. Cordycepin Attenuates IFN-γ-Induced Macrophage IP-10 and Mig Expressions by Inhibiting STAT1 Activity in CFA-Induced Inflammation Mice Model. Inflammation. 2019 Dec 23.  IHC-P ;  Mouse.   PubMed:31873836 [IF=2.148] Zhang M et al. The role of TrkA in the promoting wounding-healing effect of CD271 on epidermal stem cells. (2018) Arch. Dermatol. Res.  IHC ;  mouse.   PubMed:30209580 [IF=2.02] Jiejuan Lai. et al. Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow. Stem Cell Res. 2021 Aug;55:102477  IF,ICC ;  Mouse.   PubMed:34343826
Research Area	Cell biology  immunology  Growth factors and hormones  G protein-coupled receptor  glycoprotein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	95kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ADGRE1: 401-500/886 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Could be involved in cell-cell interactions. Subunit: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain. Subcellular Location: Cell membrane. Tissue Specificity: Wide expression; increased levels in peripheral blood mononuclear cells. Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain. SWISS: Q14246 Gene ID: 2015 Database links: Entrez Gene: 2015 Human Entrez Gene: 13733 Mouse Omim: 600493 Human SwissProt: Q14246 Human SwissProt: Q61549 Mouse Unigene: 2375 Human Unigene: 2254 Mouse
Product Picture	Sample: Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 ug Lane 2: HL60 (Human) Cell Lysate at 30 ug Primary: Anti-EMR1/ F4/80 (SL11182R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 100-110 kD Observed band size: 125 kD

Cartpieces

• 
• 1

  1Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 2

  2Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• F

  FDelete

• 
• F

  FDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout