Product Name	PCDHGA10
Chinese Name	原钙粘蛋白γ10抗体
Alias	PCDH gamma A10; PCDHGA 10; PCDHGA-10; Protocadherin gamma A10; PCDGA_HUMAN.
Research Area	Signal transduction  Cell adhesion molecule  Cytoskeleton  Extracellular matrix  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	98kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PCDHGA10: 351-450/936 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA10 (Protocadherin gamma-A10) is a 936 amino acid that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA10 is a member of the gamma subfamily A. PCDHGA10 is a type I transmembrane receptor containing six cadherin motifs and is expressed in the central nervous system where it localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGA10 that are produced as a result of alternative splicing events. Function: Potential calcium dependent cell adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subcellular Location: Cell membrane; Single pass type I membrane protein. Similarity: Contains 6 cadherin domains. SWISS: Q9Y5H3 Gene ID: 56106 Database links: Entrez Gene: 56106 Human Omim: 606297 Human SwissProt: Q9Y5H3 Human

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