Product Name	ILDR1
Chinese Name	免疫球蛋白样结构域受体1抗体
Alias	ILDR1alpha; ILDR1beta; Immunoglobulin like domain containing receptor 1 alpha; Immunoglobulin like domain containing receptor 1 alpha; Immunoglobulin like domain containing receptor 1; Immunoglobulin like domain containing receptor 1 beta; MGC50831; ILDR1_HUMAN.
literatures	Specific References  (1)     |     SL11013R has been referenced in 1 publications. [IF=6.6] Franziska Weiß. et al. MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier. CELLS-BASEL. 2022 Jan;11(9):1541  WB ;  Human.   PubMed:35563847
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=3ug/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	60kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ILDR1: 101-200/546 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ILDR1 is a putative membrane receptor. It belongs to the immunoglobulin superfamily, LISCH7 family. It is mainly expressed in prostate and to a lower extent in testis, pancreas, kidney, heart and liver. Function: Putative membrane receptor. Subunit: Homooligomer. Subcellular Location: Cell membrane; Single pass type I membrane protein. Isoform 5: Cytoplasm (cytosol). Tissue Specificity: Mainly expressed in prostate and to a lower extent in testis, pancreas, kidney, heart and liver. DISEASE: Defects in ILDR1 are the cause of deafness autosomal recessive type 42 (DFNB42) [MIM:609646]; also called non-syndromic sensorineural deafness autosomal recessive type 42. DFNB42 is a prelingual, non-progressive form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Similarity: Belongs to the immunoglobulin superfamily. LISCH7 family. Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q86SU0 Gene ID: 286676 Database links: Entrez Gene: 286676 Human Entrez Gene: 106347 Mouse Omim: 609739 Human SwissProt: Q86SU0 Human SwissProt: Q8CBR1 Mouse Unigene: 98484 Human Unigene: 17807 Mouse
Product Picture	Sample: Prostate(Rat) Cell Lysate at 40 ug Primary: Anti-ILDR1 (SL11013R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 56 kD Sample: DU145(Human) Cell Lysate at 30 ug Primary: Anti-ILDR1 (SL11013R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 56 kD Sample: Pancreas(Mouse) Cell Lysate at 40 ug Primary: Anti-ILDR1 (SL11013R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 56kD Blank control: A431. Primary Antibody (green line): Rabbit Anti-ILDR1 antibody (SL11013R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody: Goat anti-rabbit IgG-AF647 Dilution: 1μg /test. Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 0.1% PBST for 20 min at room temperature. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature.Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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