Product Name	CTR1
Chinese Name	铜离子Transporter1抗体
Alias	Copper transport 1 homolog; Copper transporter 1; COPT1; COPT1_HUMAN; hCTR1; High affinity copper uptake protein 1; SLC31A1; solute carrier family 31 (copper tansporters) member 1; Solute carrier family 31 member 1.
Research Area	Neurobiology  Channel protein  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CTR1: 51-150/190 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011] Function: High-affinity, saturable copper transporter involved in dietary copper uptake. Subunit: Homotrimer. Subcellular Location: Cell membrane. Localizes to the apical membrane in intestinal epithelial cells. Post-translational modifications: O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain. Similarity: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily. SWISS: O15431 Gene ID: 1317 Database links: Entrez Gene: 1317 Human Entrez Gene: 20529 Mouse Entrez Gene: 171135 Rat Omim: 603085 Human SwissProt: O15431 Human SwissProt: Q8K211 Mouse SwissProt: Q9JK41 Rat Unigene: 532315 Human Unigene: 248637 Mouse Unigene: 2789 Rat
Product Picture	Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CTR1 Polyclonal Antibody, Unconjugated(SL10773R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining araformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CTR1) Polyclonal Antibody, Unconjugated (SL10773R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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