Product Name	I-309/CCL1
Chinese Name	嗜酸粒细胞趋化蛋白CCL1抗体
Alias	C-C motif chemokine 1 precursor; chemokine (C-C motif) ligand 1; BF534335; I-309; Scya1; CCL1; Chemokine CC Motif Ligand 1; inflammatory cytokine I-309; P500; SCYA1; SISe; small inducible cytokine A1; T lymphocyte secreted protein I-309; TCA3.
literatures	Specific References  (1)     |     SL10709R has been referenced in 1 publications. [IF=4.128] Ito I et al. Host antibacterial defense of 6–10 Gy γ-irradiated mice subjected to lentiviral vector-based Gas5 gene therapyGene Ther.2020 Dec 1.  FC ;  Mouse.   PubMed:33262512
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	10kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human I-309/CCL1: 51-96/96
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq, Jul 2008]. Function: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Subunit: Monomer. Subcellular Location: Secreted. Similarity: Belongs to the intercrine beta (chemokine CC) family. SWISS: P22362 Gene ID: 6346 Database links: Entrez Gene: 6346 Human Omim: 182281 Human SwissProt: P22362 Human Unigene: 72918 Human
Product Picture	Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-I-309/CCL1 Polyclonal Antibody, Unconjugated(SL10709R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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