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Product Name ROR gamma T Chinese Name 维甲酸相关孤儿受体γt抗体 Alias RORG_HUMAN; Nuclear receptor ROR-gamma; ROR Gamma; NR1F3; RZRG; TOR; IMD42; RZR-GAMMA; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR-related orphan receptor C; Retinoid-related orphan receptor-gamma; ROR gamma T [Mus musculus]; nuclear receptor ROR-gamma isoform 2; RORgT; literatures Specific References (4) | SL10647R has been referenced in 4 publications.[IF=8.44] Jia, Yu. et al. The treatment of Qibai Pingfei Capsule on chronic obstructive pulmonary disease may be mediated by Th17/Treg balance and gut-lung axis microbiota. J TRANSL MED. 2022 Dec;20(1):1-21 WB, IHC ; Rat.[IF=6.78] Le Lv. et al. Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance. LIFE SCI. 2023 Apr;318:121501 WB ; Mouse.[IF=5.878] Lingling Dong. et al. Anti-inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota. 2022 Mar 01 WB ; Mouse.[IF=5.279] Yan Zhang. et al. Ganoderic Acid A To Alleviate Neuroinflammation of Alzheimer’s Disease in Mice by Regulating the Imbalance of the Th17/Tregs Axis. J Agr Food Chem. 2021;69(47):14204–14214 WB ; Mouse.Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 54kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse ROR gamma T: 51-150/518 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
SWISS:
P51449
Gene ID:
19885
Database links:Entrez Gene: 6097 Human
Entrez Gene: 19885 Mouse
Omim: 602943 Human
SwissProt: P51449 Human
SwissProt: P51450 Mouse
Unigene: 256022 Human
Unigene: 607993 Human
Unigene: 4372 Mouse
Product Picture Sample:
Muscle (mouse) Lysate at 40 ug
Kidney (mouse) Lysate at 40 ug
Primary: Anti- ROR gamma T (SL10647R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
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