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Product Name PRSS2 Chinese Name 丝氨酸蛋白酶2抗体 Alias Anionic trypsinogen; EC 3.4.21.4; MGC111183; MGC120174; Protease serine 2 preproprotein; Protease, serine, 2 (trypsin 2); Protease, serine, 2; Protease, serine, 2, preproprotein; Prss2; Serine protease 2; TRY2; TRY2_HUMAN; TRY8; TRYP2; Trypsin 2; Trypsin II; Trypsin-2; Trypsinogen 2. Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Cellular localization Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PRSS2: 21-120/247 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008].
Function:
In the ileum, may be involved in defensin processing, including DEFA5.
Subcellular Location:
Secreted, extracellular space.
Tissue Specificity:
Expressed in Paneth cells, at the base of small intestinal crypts.
Post-translational modifications:
Sulfated on tyrosine.
Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
SWISS:
P07478
Gene ID:
5645
Database links:Entrez Gene: 5645 Human
Omim: 601564 Human
SwissProt: P07478 Human
Unigene: 449281 Human
Unigene: 728780 Human
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