Product Name	PTGFR
Chinese Name	前列腺素F2a受体抗体PGF2αR
Alias	Prostaglandin F2 alpha Receptor PF2R_HUMAN; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; Prostaglandin F receptor; Prostaglandin F2-alpha receptor; Prostaglandin receptor 2 alpha; Prostanoid FP receptor; PTGFR; FP; MGC120498; MGC46203.
literatures	Specific References  (1)     |     SL10433R has been referenced in 1 publications. [IF=1.66] Xueqiang Qinet al. Effects of non-esterified fatty acids on relative abundance of prostaglandin E2 and F2α synthesis-related mRNA transcripts and protein in endometrial cells of cattle in vitro. Anim Reprod Sci . 2020 Oct;221:106549.  IF ;  Bovine.   PubMed:32861111
Research Area	Neurobiology  The cell membrane受体  G protein-coupled receptor  G protein signal  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	40kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PTGFR: 121-220/359 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P43088 Gene ID: 5737 Database links: Entrez Gene: 5737 Human Omim: 600563 Human SwissProt: P43088 Human Unigene: 654365 Human
Product Picture	Protein: U2os(human) lysates at 40ug; Primary: Anti-PTGFR (SL10433R) at 1:300; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G-HRP) at 1: 5000; ECL excitated the fluorescence; Predicted band size :40 kD Observed band size :50 kD

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