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Rabbit Anti-Delta Opioid Receptor antibody
Rabbit Anti-Delta Opioid Receptor antibody
Delta type opioid receptor; Delta type opioid receptor DOR 1; DOR 1; DOR1; mDOR; Nbor; Opioid receptor delta 1; OPRD; OPRD1; OPRD_HUMAN; Delta-type opioid receptor; D-OR-1; DOR-1.
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  • NO.:SL10396R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Mouse,(predicted: Rat,Chicken,Dog,Pig,Cow,Rabbit,Guinea Pig,)
    Applications:WB ELISA ICC IF
    concentration:1mg/ml
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Details

Product Name Delta Opioid Receptor
Chinese Name D型阿片受体抗体
Alias Delta type opioid receptor; Delta type opioid receptor DOR 1; DOR 1; DOR1; mDOR; Nbor; Opioid receptor delta 1; OPRD; OPRD1; OPRD_HUMAN; Delta-type opioid receptor; D-OR-1; DOR-1.  
literatures
Specific References  (1)     |     SL10396R has been referenced in 1 publications.
[IF=2.33] Wu, Jian, Peng Li, and Xiuying Wu. "The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats." Sleep and Breathing (2017): 1-7.  WB ;  Rat.  
Research Area Cell biology  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig, )
Applications WB=1:500-2000 ELISA=1:5000-10000 ICC=1:100-500 IF=1:100-500 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 41kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Delta Opioid Receptor: 81-180/372 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology with SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes.

Function:
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.

Subunit:
Interacts with GPRASP1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Abundant in lymphoid tissues.

Post-translational modifications:
Glycosylation is tissue specific. Sialylation of N-glycans at Asn-93 in brain and at Asn-42, Asn-93 and Asn-117 in thymus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P41143

Gene ID:
4985

Database links:

Entrez Gene: 4985 Human

Entrez Gene: 18386 Mouse

Entrez Gene: 24613 Rat

Omim: 165195 Human

SwissProt: P41143 Human

SwissProt: P32300 Mouse

SwissProt: P33533 Rat

Unigene: 372 Human

Unigene: 10310 Rat




Product Picture
Sample: heart (Mouse) Lysate at 40 ug
Primary: Anti-Delta Opioid Receptor (SL10396R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 51 kD
Sample:
liver (Mouse) Lysate at 40 ug
Primary: Anti-Delta Opioid Receptor (SL10396R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 50 kD

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