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Rabbit Anti-Alpha s2 Casein antibody
Rabbit Anti-Alpha s2 Casein antibody
Alpha-s2-Casein; CSN1S2; CASA2_BOVIN; Casocidin-1; Casocidin-I.
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  • NO.:SL10034R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Cow,Sheep,)
    Applications:WB ELISA IHC-P IHC-F
    concentration:1mg/ml
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Details

Product Name Alpha s2 Casein
Chinese Name α-s2酪蛋白抗体
Alias Alpha-s2-Casein; CSN1S2; CASA2_BOVIN; Casocidin-1; Casocidin-I.   
literatures
Specific References  (3)     |     SL10034R has been referenced in 3 publications.
[IF=7.514] Chiara Rossi. et al. Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins. Food Chem. 2022 Aug;385:132667  WB ;  Native Κ-Casein.  
[IF=4.26] Luo et al. SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells. (2018) Sci.Rep. 8:3912  WB ;  Cow.  
[IF=1.29] Gao, H. N., et al. "Leucine and histidine independently regulate milk protein synthesis in bovine mammary epithelial cells via mTOR signaling pathway." J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.) 16.6 (2015): 560-572.  WB ;  Bovine.  
Research Area immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Cow, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 24kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from cow Alpha s2 Casein: 165-203/222 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Important role in the capacity of milk to transport calcium phosphate.
Casocidin-I inhibits the growth of E.coli and S.carnosus.

Subcellular Location:
Secreted.

Tissue Specificity:
Mammary gland specific. Secreted in milk.

Similarity:
Belongs to the alpha-casein family.

SWISS:
P02663

Gene ID:
282209

Database links:
Entrez Gene: 282209 Bovine

SwissProt: P02663 Bovine



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Mouse mammary tumor); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Alpha s2 Casein ) Polyclonal Antibody, Unconjugated (SL10034R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (sp-0023) for 20 minutes and DAB staining.

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