Product Name	Alpha s1 Casein
Chinese Name	α-s1酪蛋白抗体
Alias	Alpha s1 Casein; alpha-S1-casein precursor; Alpha-S1-casein; CSN1S1; CSN1; Bos d 8; Antioxidant peptide; CASA1_BOVIN.
literatures	Specific References  (2)     |     SL10033R has been referenced in 2 publications. [IF=11.504] Sanam Foroutanparsa. et al. Spatial distribution of αs1-caseins and β-caseins in milk gels acidified with glucono-δ-lactone. FOOD HYDROCOLLOID. 2023 Jan;:108506  IF ;  Cow.   PubMed:10.1016/j.foodhyd.2023.108506 [IF=7.514] Chiara Rossi. et al. Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins. Food Chem. 2022 Aug;385:132667  WB ;  Native Κ-Casein.   PubMed:35299016
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Cow, Sheep, )
Applications	ELISA=1:5000-10000 IHC-F=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from cow Alpha s1 Casein: 75-214/214
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	alpha-S1-casein, also known as CSN1S1, CSN1 or CASA, is a 185 amino acid secreted protein that is mammary gland-specific and belongs to the alpha-casein family. Existing as a disulfide-linked heterodimer with ⅹ-casein, alpha-S1-casein plays an important role in the ability of milk to transport calcium phosphate, a family of minerals that are key components of bone and teeth. alpha-S1-casein exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a region on human chromosome 4 that encodes other casein family members. Chromosome 4 houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: Important role in the capacity of milk to transport calcium phosphate. Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity. Subcellular Location: Secreted. Tissue Specificity: Mammary gland specific. Secreted in milk. Similarity: Belongs to the alpha-casein family. SWISS: P02662 Gene ID: 282208 Database links: Entrez Gene: 282208 Bovin Entrez Gene: 1446 Human Omim: 115450 Human SwissProt: P47710 Human SwissProt: P02662 Bovin Unigene: 3155 Human

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