Product Name	AVPR2
Chinese Name	精氨酸加压素受体2抗体
Alias	arginine vasopressin receptor 2; ADHR; Antidiuretic hormone recepto; Arginine vasopressin receptor 2; AVP R2; AVPR 2; AVPR V2; DI1; DIR 3; DIR; DIR3; MGC126533; MGC138386; NDI; Nephrogenic diabetes insipidus; Renal type arginine vasopressin recepto; V2R; Vasopressin V2 receptor.
literatures	Specific References  (1)     |     SL10014R has been referenced in 1 publications. [IF=4.012] Nagano H et al. Muscarinic M receptor promotes vasopressin synthesis in mice supraoptic nuclei. J Endocrinol. 2018 May;237(2):207-216.  IHC-P ;  Mouse.   PubMed:29563233
Research Area	Cell biology  Growth factors and hormones  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	40kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human AVPR2: 65-170/371 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	AVPR2 is a receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. AVPR2 is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The AVPR2 receptor is also expressed outside the kidney although its tissue localization is uncertain. Function: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Kidney. Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. SWISS: P30518 Gene ID: 554 Database links: Entrez Gene: 554 Human Entrez Gene: 12000 Mouse Entrez Gene: 25108 Rat Omim: 300538 Human SwissProt: P30518 Human SwissProt: O88721 Mouse SwissProt: Q00788 Rat Unigene: 567240 Human Unigene: 383171 Mouse Unigene: 209041 Rat
Product Picture	Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-AVPR2 (SL10014R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 50 kD Blank control:U937. Primary Antibody (green line): Rabbit Anti-AVPR2 antibody (SL10014R) Dilution: 2μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells wereincubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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