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Product Name SLC34A2 Chinese Name 磷酸钠协同Transporter抗体 Alias NaPi-2b; Sodium-dependent phosphate transport protein 2B; Sodium/phosphatecotransporter 2B; Na(+)/Pi cotransporter 2B; Sodium-phosphatetransport protein 2B; Na(+)-dependent phosphate cotransporter 2B; Solute carrier family 34 member 2; NPT2B_MOUSE. Research Area Cell biology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Mouse, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 77kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse SLC34A2: 265-350/697 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Na+/Pi-cotransporterThis is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows reabsorption of filtered Pi in the proximal tubule.
Function:
May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Highly abundant in the ileum of small intestine, whereas it is almost absent in the duodenum and in the jejunum.
Similarity:
Belongs to the SLC34A transporter family.
SWISS:
Q9DBP0
Gene ID:
20531
Database links:Entrez Gene: 10568 Human
Entrez Gene: 20531 Mouse
Omim: 604217 Human
SwissProt: O95436 Human
Unigene: 479372 Human
SLC34A2/NaPi-2b是磷酸钠协同Transporter的基因,表达在动物多种组织中,以肺组织表达最高。该基因主要参与无机磷代谢,与肺泡微石症、睾丸微石症等多种代谢性疾病发病相关。
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