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Product Name hCG beta Chinese Name 人β亚基人绒毛膜促性腺激素(β HCG)抗体 Alias HCG beta; Beta-HCG; Anterior pituitary glycoprotein hormones common subunit alpha; beta-HCG; CG ALPHA; CG beta a; CG beta; CGA; CGB; CGB1; CGB2; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin alpha chain; Choriogonadotropin subunit beta; Chorionic gonadotrophin alpha subunit; Chorionic gonadotrophin chain beta; Chorionic gonadotropin alpha polypeptide; Chorionic gonadotropin beta 5 subunit; Chorionic gonadotropin beta 7 subunit; Chorionic gonadotropin beta 8 subunit; Chorionic gonadotropin beta chain; Chorionic gonadotropin beta polypeptide 1; Chorionic gonadotropin beta polypeptide 2; Chorionic gonadotropin beta polypeptide 5; Chorionic gonadotropin beta polypeptide 7; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta subunit; CGHB_HUMAN literatures Specific References (1) | SL0953R has been referenced in 1 publications.[IF=7.48] Zong, Chen, et al. "Multilayer hemin/G-quadruplex wrapped gold nanoparticles as tag for ultrasensitive multiplex immunoassay by chemiluminescence imaging." Biosensors and Bioelectronics 43 (2013): 372-378. ELISA ;Research Area Tumour immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 16kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Beta-HCG: 81-165/165 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq].
Function:
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
Subcellular Location:
Secreted.
Tissue Specificity:
Placenta.
Similarity:
Belongs to the glycoprotein hormones subunit beta family.
SWISS:
P01233
Gene ID:
1082
Database links:Entrez Gene: 1082 Human
Entrez Gene: 93659 Human
Entrez Gene: 94027 Human
Entrez Gene: 94115 Human
Omim: 118860 Human
SwissProt: P01233 Human
SwissProt: Q6NT52 Human
Unigene: 172944 Human
Unigene: 446683 Human
Unigene: 590955 Human
Unigene: 659014 Human
Unigene: 681647 Human
Unigene: 743279 Human
Unigene: 745468 Human
HCG是由胎盘合体滋养层细胞产生的一种glycoprotein激素,HCG-β主要用于胎盘滋养细胞和生殖细胞Tumour如葡萄胎、绒癌的诊断和辅助诊断。
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