Product Name	HLA G
Chinese Name	人类白细胞抗原G抗体
Alias	B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA 60; HLA class I histocompatibility antigen alpha chain G; HLA class I histocompatibility antigen alpha chain G precursor; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G; HLA G antigen; HLA G histocompatibility antigen class I G; HLA G protein; HLA G2.2; HLA G3; HLA-G; HLA-G histocompatibility antigen, class I; HLA60; HLAG; HLAG_HUMAN; Human Leukocyte Antigen G Histocompatability Antigen Class 1; Lymphocyte antigen; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC class Ib antigen; MHC G; Murine homolog of Qa; T Cell A Locus; T-cell A locus; TCA.
literatures	Specific References  (2)     |     SL0752R has been referenced in 2 publications. [IF=3.762] Sanchez-Ruiz M et al. Enteric murine ganglionitis induced by autoimmune CD8 T cells mimics human gastrointestinal dysmotility. Am J Pathol. 2019 Mar;189(3):540-551.  IHC&IHF ;  Human.   PubMed:30593823 [IF=1.894] Tan H et al. Is Atrial Natriuretic Peptide (ANP) and Natriuretic Peptide Receptor-A (NPR-A) Expression in Human Placenta and Decidua Normal? Med Sci Monit. 2019 Apr 19;25:2868-2878.  IHC-P ;  Human.   PubMed:31000687
Research Area	immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	35kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from the middle of human HLA-G: 181-280/338 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] Subunit: Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Homodimer; disulfide-linked. Binds to LILRB1 and LILRB2. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in trophoblasts. Similarity: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) SWISS: P17693 Gene ID: 3135 Database links: Entrez Gene: 3135 Human Omim: 142871 Human SwissProt: P17693 Human Unigene: 512152 Human 人类白细胞抗原G/组织相容性白细胞抗原G(Human Leukocyte Antigen-G, HLA-G )是一种非典型的白细胞抗原Ⅰ族组织相溶性抗原。该抗原在正常情况下仅在胎盘的绒毛膜表达。在病理情况下HLA-G只在某些癌细胞表达，在正常组织或良性Tumour则很少表达.因此, HLA-G是一个具有高度Tumour特异性的TumourMaker。 近年研究认为HLA—G作为免疫耐受分子，在Tumour免疫逃逸中可能具有重要作用.
Product Picture	Sample: Brain (Rat) Lysate at 30 ug Kidney (Rat) lysate at 30 ug Primary: Anti- HLA G (SL0752R) at 1/200 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (SL0295G-HRP) at 1/3000 dilution Predicted band size: 35 kD Observed band size: 35 kD Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-HLA B/HLA G Polyclonal Antibody, Unconjugated(SL0752R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

Cartpieces

• 
• 1

  1Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 6

  6Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• B

  BDelete

• 
• B

  BDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout