Product Name	CEAcam8
Chinese Name	癌胚抗原相关Cell adhesion molecule8抗体
Alias	Carcinoembryonic Antigen CGM6; Carcinoembryonic antigen gene family member 6; Carcinoembryonic Antigen Related Cell Adhesion Molecule 8; CD 66b; CD 67; CD66b antigen; CD67; CD67 antigen; CEACAM 8; CEACAM8; CGM 6; CGM6; NCA 95; NCA95; Nonspecific cross reacting antigen NCA 95; Non-specific -reacting antigen NCA-95; Nonspecific cross reacting antigen NCA95; CEAM8_HUMAN; Carcinoembryonic antigen-related cell adhesion molecule 8; CD66b.
literatures	Specific References  (1)     |     SL0744R has been referenced in 1 publications. [IF=8.537] Zhan et al. Optimization of optical excitation of upconversion nanoparticles for rapid microscopy and deeper tissue imaging with higher quantum yield. (2013) Theranostics. 3:306-16  Human.   PubMed:23650478
Research Area	Tumour  Cell biology  Cell adhesion molecule  Cell Surface Molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CEAcam8: 51-150/349
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is a highly glycosylated protein expressed only in neutrophils and eosinophils in humans. The precise function of CEACAM8 remains unclear. As a member of the family of carcinoembryonic antigen (CEA), it may play a role in the interaction between granulocytes or between granulocytes and epithelial cells. Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. Similarity: Belongs to the immunoglobulin superfamily. CEA family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: P31997 Gene ID: 1088 Database links: Entrez Gene: 1088 Human SwissProt: P31997 Human Unigene: 41 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (human rectal carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CEAcam8) Polyclonal Antibody, Unconjugated (SL0744R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CEAcam8) Polyclonal Antibody, Unconjugated (SL0744R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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