Product Name	Spindlin 1
Chinese Name	卵巢癌相关蛋白抗体
Alias	Spindlin-like protein 2; SPIN-2; DXF34; OCR; Ovarian cancer-related protein; SPIN; Spin1; SPIN1_HUMAN; Spindlin-1.
Research Area	Tumour  Cell biology  Developmental biology  Signal transduction  Cyclin  Cell differentiation  TumourCell biologyMaker  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	29kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Spindin 1: 3-100/237
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Spindlin 1 (Spindlin-like protein 2; SPIN-2 ) protein May play a role in cell-cycle regulation during the transition from gamete to embryo. Subcellular location in the Nucleus. Belongs to the SPIN/STSY family. Function: May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). Subunit: Homodimer; may form higher-order oligomers. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated during oocyte meiotic maturation. Similarity: Belongs to the SPIN/STSY family. SWISS: Q9Y657 Gene ID: 10927 Database links: Entrez Gene: 10927 Human Omim: 609936 Human SwissProt: Q9Y657 Human Unigene: 146804 Human spindlin1又称：DXF34 经研究发现，可能是一种与Tumour形成相关的原癌基因.
Product Picture	Tissue/cell: Human Cervical Cancer tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Spindlin 1 Polyclonal Antibody, Unconjugated(SL0724R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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