Product Name	PEPT1
Chinese Name	肠道肽Transporter1/小肽Transporter1抗体
Alias	SLC15A1; Oligopeptide transporter, small intestine isoform; Peptide transporter 1; Intestinal H(+)/peptide cotransporter; Solute carrier family 15 member 1(SLC15A1); +peptide cotransporter; HPECT1; HPEPT1; Human peptide transporter (HPEPT1) mRNA complete cds; Intestinal H; Oligopeptide transporter small intestine isoform; PEPT1; Peptide transporter 1; Solute carrier family 15 (oligopeptide transporter) member 1; S15A1_HUMAN.
literatures	Specific References  (5)     |     SL0689R has been referenced in 5 publications. [IF=10.317] Yaxian Zheng. et al. Tailored elasticity combined with biomimetic surface promotes nanoparticle transcytosis to overcome mucosal epithelial barrier. Biomaterials. 2020 Dec;262:120323  IF ;  Human.   PubMed:32896816 [IF=7.514] Yi Wu. et al. Selective transportation and energy homeostasis regulation of dietary advanced glycation end-products in human intestinal Caco-2 cells. FOOD CHEM. 2022 Oct;391:133284  FC ;  Human.   PubMed:35640343 [IF=6.383] Yang Wen. et al. Different copper sources and levels affect growth performance, copper content, carcass characteristics, intestinal microorganism and metabolism of finishing pigs. Anim Nutr. 2021 Nov;:  WB ;  Pig.   PubMed:10.1016/j.aninu.2021.10.007 [IF=3.73] Xu, Qingbiao, et al. "Establishment and Characterization of an Omasal Epithelial Cell Model Derived from Dairy Calves for the Study of Small Peptide Absorption." PLOS ONE 9.3 (2014): e88993.  Bovine.   PubMed:24633419 [IF=3.357] Morita M et al. Fluorescence‐based discrimination of breast cancer cells by direct exposure to 5‐aminolevulinic acid. Cancer Med. 2019 Aug 5.  WB ;  Human.   PubMed:31385432
Research Area	Signal transduction  Channel protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=2μg/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	79kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PEPT1: 101-200/714(chk) <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	PEPT1(Oligopeptide transporter, small intestine isoform (Peptide transporter 1) (Intestinal H(+)/peptide cotransporter) (Solute carrier family 15 member 1) Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Subcellular Location：membrane; Multi-pass membrane protein. Tissue Specificity Intestine, kidney, liver and low in brain. Belongs to the PTR2/POT transporter (TC 2.A.17) family. Function: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. SWISS: Q90WH8 Gene ID: 6564 Database links: Entrez Gene: 6564 Human Omim: 600544 Human SwissProt: P46059 Human Unigene: 436893 Human 小肽Transporter又称寡肽Transporter; 小肽是蛋白质在动物体内消化的主要产物，而位于小肠刷状缘膜上的小肽Transporter 在小肽的吸收过程中发挥重要作用，因此PepT1的活性直接影响小肽的吸收。 PepT1主要在消化道中表达，在肾脏中也有微弱的表达。PepT1是低親和力、高容量的肽載體PepT2是高親和力、低容量的肽載體。PepT2主要在腎臟中表達。
Product Picture	Black line : Positive blank control SH-Sy5Y); Negative blank control (A431） Green line : Primary Antibody (Rabbit Anti-PEPT1 antibody (SL0689R) ) Orange line：Isotype Control Antibody (Rabbit IgG) . Blue line : Secondary Antibody (Goat anti-rabbit IgG-AF488) SH-Sy5Y（Positive）and A431（Negative control）cells (black) were incubated in 5% BSA blocking buffer for 30 min at room temperature. Cells were then stained with PEPT1 Antibody(SL0689R)at 1:50 dilution in blocking buffer and incubated for 30 min at room temperature, washed twice with 2% BSA in PBS, followed by secondary antibody(blue) incubation for 40 min at room temperature. Acquisitions of 20,000 events were performed. Cells stained with primary antibody (green), and isotype control (orange). Blank control: HCCLM3(blue) Isotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:100 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 3μl in 100 μL1X PBS containing 0.5% BSA(green).

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