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Rabbit Anti-Estrogen Sulfotransferase antibody
Rabbit Anti-Estrogen Sulfotransferase antibody
Estrogen Sulfotransferase; Ste; SULT1E1; Estrogen sulfotransferase, testis isoform; Sulfotransferase, estrogen-preferring; EST; EST1; STE; sulfotransferase family 1E, estrogen-preferring, member 1; Sulfotransferase estrogen preferring; ST1E1_HUMAN.
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  • NO.:SL0629R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Dog,Pig,Horse,Rabbit,)
    Applications:WB ELISA
    concentration:1mg/ml
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Details

Product Name Estrogen Sulfotransferase
Chinese Name 雌激素硫酸转移酶抗体
Alias Estrogen Sulfotransferase; Ste; SULT1E1; Estrogen sulfotransferase, testis isoform; Sulfotransferase, estrogen-preferring; EST; EST1; STE; sulfotransferase family 1E, estrogen-preferring, member 1; Sulfotransferase estrogen preferring; ST1E1_HUMAN.  
Research Area immunology  Growth factors and hormones  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Dog, Pig, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 32kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Estrogen Sulfotranferase: 51-145/294 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.

Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Liver, intestine and at lower level in the kidney.

Similarity:
Belongs to the sulfotransferase 1 family.

SWISS:
P49888

Gene ID:
6783

Database links:

Entrez Gene: 6783 Human

Entrez Gene: 25355 Rat

Omim: 600043 Human

SwissProt: P49888 Human

SwissProt: P52844 Rat

Unigene: 479898 Human



Product Picture
Sample:
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti-Estrogen Sulfotransferase (SL0629R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 32 kD

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