Product Name	ZNF300
Chinese Name	Zinc finger protein300抗体
Alias	Kruppel like zinc finger protein; Zinc finger protein 300; ZN300_HUMAN.
literatures	Specific References  (1)     |     SL0628R has been referenced in 1 publications. [IF=1.291] Xue et al. ZNF300, a recently identified human transcription factor, activates the human IL-2Rβ promoter through the overlapping ZNF300/EGR1 binding site. (2010) Cell.Mol.Biol.Lett. 15:530-40  WB ;   PubMed:20585888
Research Area	Chromatin and nuclear signals  Signal transduction  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	68kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZNF300: 165-250/604
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ZNF300 contains C2H2 (or Kruppel)-type zinc finger motifs that tetrahedrally coordinate zinc ions and form a protein structure that can bind DNA and regulate transcription (Gou et al.,2004 [PubMed 14746915]). ZNF300 belongs to the krueppel C2H2 type zinc finger protein family. It contains twelve C2H2 type zinc fingers and one KRAB domain. ZNF300 has a transcriptional repressor activity. Expressed mostly in heart, skeletal muscle and brain. Isoforms 1 and 2 are highly expressed in testis. There are three named isoforms. Function: Has a transcriptional repressor activity. Subcellular Location: Nucleus. Tissue Specificity: Expressed mostly in heart, skeletal muscle and brain. Isoform 1 and isoform 2 are highly expressed in testis. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 12 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: Q96RE9 Gene ID: 91975 Database links: Entrez Gene: 91975 Human Omim: 612429 Human SwissProt: Q96RE9 Human Unigene: 134885 Human ZNF300白血病相关性研究。
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-ZNF300 (SL0628R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68 kD Observed band size: 68 kD Sample: Lane1: Testis (Mouse) Lysate at 30 ug Lane2: Small intestine (Mouse) Lysate at 30 ug Primary: Anti-ZNF300(SL0628R) at 1:200 dilution; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(SL0295G-HRP) at 1:3000 dilution; Predicted band size : 66kD Observed band size : 70,66kD

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