Product Name	CYGB
Chinese Name	细胞球蛋白抗体
Alias	Cytoglobin; HGB; STAP; Histoglobin; HGb; cell activation-associated protein; CYGB_HUMAN.
literatures	Specific References  (1)     |     SL0590R has been referenced in 1 publications. [IF=3.33] Xu, Hong-Wu, et al. "The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients." BMC cancer 13.1 (2013): 247.  IHC-P ;  Human.   PubMed:23688241
Research Area	Cell biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Chicken, Dog, Cow, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human cytoglobin: 87-132/190
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012] Function: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Subunit: Homodimer; disulfide-linked. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. Similarity: Belongs to the globin family. SWISS: Q8WWM9 Gene ID: 114757 Database links: Entrez Gene: 609341 Dog Entrez Gene: 114757 Human Entrez Gene: 114886 Mouse Entrez Gene: 170520 Rat SwissProt: Q8WWM9 Human SwissProt: Q9CX80 Mouse SwissProt: Q921A4 Rat 细胞球蛋白Cygb是最近发现的脊椎动物球蛋白超家族的一员,在体内分布广泛。 有学者认为：Cygb的确切功能尚不十分清楚,目前主要有携氧与储氧、氧感受器、活性氧基团和NO的清道夫、NADH氧化酶或过氧化氢酶样作用和参与胶原形成等假说。
Product Picture	Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Cygb Polyclonal Antibody, Unconjugated(SL0590R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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