Product Name	ANGPTL2
Chinese Name	血管生成素样蛋白2抗体
Alias	ANGPTL2; Angiopoietin like 2; Angiopoietin related protein 2; Angiopoietin-like protein 2; Angiopoietin-related protein 2; ANGL2_HUMAN; Angptl2; ANGL2; Arp2; HARP; MGC8889.
Research Area	Tumour  Cardiovascular
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	55kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ANGPTL2: 401-493/493
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ANGPTL2/ANG-2 (Angiopoietin-like Protein 2) Induces sprouting in endothelial cells through an autocrine and paracrine action. [Subcellular location] Secreted. [Tissue specificity] Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate. [PTM] N-glycosylated. [Similarity] Contains 1 fibrinogen C-terminal domain. ANGPTL2/ANG-2 (Angiopoietin-like Protein 2). Function: Induces sprouting in endothelial cells through an autocrine and paracrine action. Subcellular Location: Secreted. Tissue Specificity: Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate. Similarity: Contains 1 fibrinogen C-terminal domain. SWISS: Q9UKU9 Gene ID: 23452 Database links: Entrez Gene: 23452 Human Entrez Gene: 26360 Mouse Entrez Gene: 171100 Rat Omim: 605001 Human SwissProt: Q9UKU9 Human SwissProt: Q9R045 Mouse Unigene: 653262 Human Unigene: 208919 Mouse Unigene: 162660 Rat Ang1/2与血管生成关系最为密切,目前有关该家族成员在Tumour血管生成中的研究正日益增多。近年来也用于Diabetes导致的血管损伤研究也是热门课题.
Product Picture	Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-ANGPTL2 (SL0537R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD Paraformaldehyde-fixed, paraffin embedded (Human uterine muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angptl2) Polyclonal Antibody, Unconjugated (SL0537R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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