Product Name	PRL
Chinese Name	泌乳素抗体
Alias	Luteotropic Hormone; Mammotropin; OTTHUMP00000017727; PRL; Prolactin; Prolactin precursor; PRL_HUMAN.
literatures	Specific References  (5)     |     SL0508R has been referenced in 5 publications. [IF=3.32] Hu, Bin, et al. "IFN?\?? Inhibits Osteopontin Expression in Human Decidual Stromal Cells and can be Attenuated by 1??, 25?\Dihydroxyvitamin D3."rican Journal of Reproductive Immunology 68.4 (2012): 353-361..rch  Human.   PubMed:22784028 [IF=2.425] Xie W et al. Seasonal expressions of prolactin, prolactin receptor and STAT5 in the scented glands of the male muskrats (Ondatra zibethicus). Eur J Histochem. 2019 Jan 17;63(1).  IHC-P ;  muskrat.   PubMed:30652434 [IF=1.785] An J et al. A clinical and basic study of optimal endometrial preparation protocols for patients with infertility undergoing frozen‑thawed embryo transfer. Exp Ther Med . 2020 Sep;20(3):2191-2199.  WB ;  Human.   PubMed:32765695 [IF=1.785] Junxia An. et al. A clinical and basic study of optimal endometrial preparation protocols for patients with infertility undergoing frozen‑thawed embryo transfer. Exp Ther Med. 2020 Sep;20(3):2191-2199  WB ;  Human.   PubMed:32765695 [IF=0.352] Xu, Qian, et al. "CYCLIN G1 INHIBITS THE PROLIFERATION OF MOUSE ENDOMETRIAL STROMAL CELL IN DECIDUALIZATION."Arch Biol Sci. 2017;69(1):71-81.  IF(ICC) ;  Mouse.   PubMed:DOI:10.2298/ABS160124080X
Research Area	Cell biology  Signal transduction  Growth factors and hormones  Kinases and Phosphatases  Endocrinopathy
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Mouse, Chicken, Pig, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	24kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PRL: 165-227/227
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. Function: Prolactin acts primarily on the mammary gland by promoting lactation. Subcellular Location: Secreted. Similarity: Belongs to the somatotropin/prolactin family. SWISS: P01236 Gene ID: 5617 Database links: Entrez Gene: 5617 Human Entrez Gene: 19109 Mouse Entrez Gene: 24683 Rat Omim: 176760 Human SwissProt: P01236 Human SwissProt: P06879 Mouse SwissProt: P01237 Rat
Product Picture	Sample: A549 cell(human) Lysate at 40 ug Primary: Anti-PRL (SL0508R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24kD Observed band size: 30 kD Tissue/cell: human placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-PRL Polyclonal Antibody, Unconjugated(SL0508R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-PRL Polyclonal Antibody, Unconjugated(SL0508R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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