Product Name	SLC1A5
Chinese Name	溶质携带物家族-1抗体
Alias	(glutamate transporter), member 7; R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; FLJ31068; Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5; Neutral amino acid transporter B(0); ATB(0); RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; AAAT_HUMAN.
literatures	Specific References  (3)     |     SL0473R has been referenced in 3 publications. [IF=5.168] Díaz-Carballo et al. Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells. (2017) Oncotarget. 8:95945-95964  FCM ;  Human.   PubMed:29221178 [IF=2.976] Guo H et al. Clinical associations between ASCT2 and p-mTOR in the pathogenesis and prognosis of epithelial ovarian cancer. Oncol Rep. 2018 Dec;40(6):3725-3733.  WB&IHC-P ;  Human.   PubMed:30272366 [IF=1.78] Huang, Fang, et al. "Upregulated SLC1A5 promotes cell growth and survival in colorectal cancer." International Journal of Clinical and Experimental Pathology 7.9 (2014): 6006.  IHC-P ;  Human.   PubMed:25337245
Research Area	Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	56kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC1A5: 465-515/541
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	solute carrier family 1 (neutral amino acid transporter), member 5. mediates infections of RD114 feline endogenous virus, baboon endogenous virus and type D simian retroviruses; baboon M7 virus receptor; RD114 virus receptor; neutral amino acid transporter B. Function: Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses. Subcellular Location: Membrane; Multi-pass membrane protein (Probable). Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Tissue Specificity: Placenta, lung, skeletal muscle, kidney, pancreas, and intestine. Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A5 subfamily. SWISS: Q15758 Gene ID: 6510 Database links: Entrez Gene: 6510 Human Entrez Gene: 20514 Mouse Entrez Gene: 292657 Rat Omim: 109190 Human SwissProt: Q15758 Human SwissProt: P51912 Mouse SwissProt: Q9Z1J7 Rat Unigene: 631582 Human Unigene: 1056 Mouse
Product Picture	Blank control: A549. Primary Antibody (green line): Rabbit Anti-SLC1A5 antibody (SL0473R) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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