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Rabbit Anti-Rarres3/Cy5.5 Conjugated antibody
Rabbit Anti-Rarres3/Cy5.5 Conjugated antibody
Retinoic acid receptor responder protein 3; HRASLS4; MGC8906; RAR responsive protein TIG3; Retinic acid inducible gene 1; Retinoic acid receptor responder (tazarotene induced) 3; Retinoid inducible gene 1 protein; RIG 1; rig1; Tazarotene induced gene 3 pr
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Product Name Anti-Rarres3/Cy5.5
Chinese Name Cy5.5标记的视黄酸受体应答蛋白3抗体
Alias Retinoic acid receptor responder protein 3; HRASLS4; MGC8906; RAR responsive protein TIG3; Retinic acid inducible gene 1; Retinoic acid receptor responder (tazarotene induced) 3; Retinoid inducible gene 1 protein; RIG 1; rig1; Tazarotene induced gene 3 protein; TIG 3; TIG3; p18H-rev 107; Group XVI phospholipase A2; HRAS-like; rCG47447; HRSL4_HUMAN; HRAS-like suppressor 4; HRSL4; RAR-responsive protein TIG3; Retinoid-inducible gene 1 protein.  
Research Area Cardiovascular  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Dog, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 18kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Rarres3
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008].

Function:
Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable.

Subcellular Location:
Membrane; Single-pass membrane protein.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the H-rev107 family.

Database links:

Entrez Gene: 5920 Human

Omim: 605092 Human

SwissProt: Q9UL19 Human

Unigene: 17466 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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