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Rabbit Anti-HOXA10/Cy5.5 Conjugated antibody
Rabbit Anti-HOXA10/Cy5.5 Conjugated antibody
Centaurin alpha 1 like; Homeo box A10; Homeobox A10; Homeobox protein 1H; Homeobox protein Hox A10; Homeobox protein HOXA10; HOX 1; HOX 1.8; HOX 1H; HOX A10; HOX1; HOX1.8; HOX1H; HOXA 10; HOXA10 protein; MGC12859; PL.
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Product Name Anti-HOXA10/Cy5.5
Chinese Name Cy5.5标记的HOXA10抗体
Alias Centaurin alpha 1 like; Homeo box A10; Homeobox A10; Homeobox protein 1H; Homeobox protein Hox A10; Homeobox protein HOXA10; HOX 1; HOX 1.8; HOX 1H; HOX A10; HOX1; HOX1.8; HOX1H; HOXA 10; HOXA10 protein; MGC12859; PL.  
Research Area Cell biology  immunology  Growth factors and hormones  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 42kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HOXA10
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. [provided by RefSeq, Mar 2011].

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 482373 Dog

Entrez Gene: 3206 Human

Entrez Gene: 15395 Mouse

Omim: 142957 Human

SwissProt: P31260 Human

SwissProt: P31310 Mouse

SwissProt: Q80Y22 Mouse

Unigene: 110637 Human

Unigene: 659350 Human

Unigene: 5 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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