Product Name	Anti-PDE9A/AP
Chinese Name	碱性磷酸酶（AP）标记的磷酸二酯酶9A抗体
Alias	5''-cyclic phosphodiesterase 9A; cGMP specific 3' 5' cyclic phosphodiesterase type 9; CGMP-specific 3'5'-cyclic phosphodiesterase type 9; FLJ90181; High affinity cGMP-specific 3''; High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A; HSPDE9A2; OTTHUMP00000109399; PDE 9A; Pde9a; PDE9A_HUMAN; Phosphodiesterase 9A; phosphodiesterase PDE9A21.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Pig, Cow, Sheep, )
Applications	WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70-73kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PDE9A
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Subcellular Location: Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum. Tissue Specificity: Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily. Database links: Entrez Gene: 5152 Human Entrez Gene: 18585 Mouse Entrez Gene: 191569 Rat GenBank: NP_001001567.1 Human Omim: 602973 Human SwissProt: O76083 Human SwissProt: O76083-2 Human SwissProt: O70628 Mouse Unigene: 473927 Human Unigene: 10812 Mouse Unigene: 20981 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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