Product Name	Anti-PSMD13/AP
Chinese Name	碱性磷酸酶（AP）标记的26S蛋白酶体非ATP酶调节亚基13抗体
Alias	26S proteasome non ATPase regulatory subunit 13; 26S proteasome non-ATPase regulatory subunit 13; 26S proteasome regulatory subunit p40.5; 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome subunit p40.5; HSPC027; P40.5; Proteasome (prosome, macropain) 26S subunit, non ATPase, 13; PSD13_HUMAN; psmD13; Rpn9; S11.
Research Area	Cell biology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Cow, )
Applications	WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	43kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PSMD13
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Subunit: Component of the PA700 complex. Similarity: Belongs to the proteasome subunit S11 family. Contains 1 PCI domain. Database links: Entrez Gene: 5719 Human Entrez Gene: 450913 Chimpanzee Entrez Gene: 513525 Cow Entrez Gene: 447560 Xenopus laevis Entrez Gene: 447992 Xenopus tropicalis Omim: 603481 Human SwissProt: Q5E964 Cow SwissProt: Q9UNM6 Human Unigene: 134688 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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