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Product Name Anti-Relaxin 3/AP Chinese Name 碱性磷酸酶(AP)标记的松弛素3抗体 Alias H3; INSL 7; INSL7; Insulin like 7; Insulin like peptide 7; Insulin like peptide INSL7; Insulin like7; Insulinlike 7; Prorelaxin H3; Prorelaxin M3; REL 3; REL3; Relaxin 3; Relaxin 3 (H3); Relaxin 3 A chain; Relaxin 3 precursor; Relaxin3; RLN 3; RLN3; RXN 3; RXN3; ZINS 4; ZINS4; REL3_HUMAN. Research Area Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 3kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Relaxin 3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes.
Function:
May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).
Subunit:
Heterodimer of a B chain and an A chain linked by two disulfide bonds.
Subcellular Location:
Secreted.
Similarity:
Belongs to the insulin family.
Database links:Entrez Gene: 117579 Human
Omim: 606855 Human
SwissProt: Q8WXF3 Human
Unigene: 352155 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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