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Product Name Anti-gamma Endorphin/AP Chinese Name 碱性磷酸酶(AP)标记的γ-内啡肽抗体 Alias COLI_HUMAN; Endorphin, gamma; Lipotropin 61-77. Research Area Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) Applications IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 1.9kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human gamma Endorphin Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Gamma-endorphin is a polypeptide that is characterized by the presence of 17 amino acids, only one more than alpha-endorphin. Similar to other endorphins, research focusing upon gamma-endorphin has been ongoing since its discovery in the 1970s. However, most of the information about the its exact role within the body is speculation that has yet to be proven. Some studies have indicated, that the polypeptide has antipsychotic effects on a certain category of patients suffering from schizophrenia, while others suggest that gamma-endorphin may act to help regulate blood pressure.
Function:
ACTH stimulates the adrenal glands to release cortisol.
MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.
Beta-endorphin and Met-enkephalin are endogenous opiates.
Subcellular Location:
Secreted.
Similarity:
Belongs to the POMC family.
Database links:Entrez Gene: 5443 Human
Entrez Gene: 18976 Mouse
Omim: 176830 Human
SwissProt: P01189 Human
SwissProt: P01193 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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