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Product Name Anti-FUT10/AP Chinese Name 碱性磷酸酶(AP)标记的FUT10蛋白抗体 Alias 3)-fucosyltransferase 10; Alpha-(1; Alpha-(1,3)-fucosyltransferase 10; Fuc-TX; Fucosyltransferase 10; Fucosyltransferase X; FucT-X; fut10; FUT10_HUMAN; Galactoside 3-L-fucosyltransferase 10. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Sheep, Chimpanzee, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 56kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FUT10 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. Product Detail background:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion, molecule recruitment and cell trafficking. Localized to the Golgi apparatus as a single-pass transmembrane protein, FucT-X, also designated ?(1,3)-fucosyltransferase 10 or FUT10, is a 479 amino acid protein that is involved in protein modification and glycosylation. There are seven isoforms of FucT-X that are produced as a result of alternative splicing events.
Function:
Probable fucosyltransferase.
Subcellular Location:
Golgi apparatus; Golgi stack membrane.
Similarity:
Belongs to the glycosyltransferase 10 family.
Database links:Entrez Gene: 84750 Human
Entrez Gene: 100444252 Orangutan
Entrez Gene: 697659 Rhesus monkey
SwissProt: Q6P4F1 Human
Unigene: 458713 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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