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Product Name Anti-RAB11FIP5/AF647 Chinese Name AF647标记的Rab11家族相互作用蛋白5抗体 Alias GAF 1; Gaf-1; GAF1; gamma SNAP associated factor 1; Gamma-SNAP-associated factor 1; KIAA0857; Phosphoprotein pp75; pp75; RAB11 family interacting protein 5 (class I); Rab11 family-interacting protein 5; Rab11 FIP5; Rab11 interacting protein; Rab11 interacting protein Rip11; Rab11-FIP5; Rab11-interacting protein Rip11; Rab11fip5; RFIP5_HUMAN; RIP11. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Monkey, Chimpanzee, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 70kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RAB11FIP5 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane.
Subcellular Location:
Cytoplasm. Recycling endosome membrane. Mitochondrion membrane.
Tissue Specificity:
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
Post-translational modifications:
Phosphorylated on serine and threonine residues.
Similarity:
Contains 1 C2 domain.
Contains 1 FIP-RBD domain.
Database links:
Entrez Gene: 740006 Chimpanzee
Entrez Gene: 102125880 Cynomolgus Monkey
Entrez Gene: 101129368 Gorilla
Entrez Gene: 26056 Human
Entrez Gene: 52055 Mouse
Entrez Gene: 100174549 Orangutan
Omim: 605536 Human
SwissProt: Q9BXF6 Human
SwissProt: Q8R361 Mouse
Unigene: 24557 Human
Unigene: 220334 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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