Product Name	Anti-TGM3/AF594
Chinese Name	AF594标记的谷氨酰胺转胺酶3抗体
Alias	Transglutaminase 3; E polypeptide protein glutamine gamma glutamyltransferase; MGC126249; MGC126250; Protein glutamine gamma glutamyltransferase E 27 kDa catalytic chain; Protein glutamine gamma glutamyltransferase E 50 kDa noncatalytic chain; Protein glutamine gamma glutamyltransferase E; TG(E); TGase E; TGE; TGM 3; TGM3; Transglutaminase E; Transglutaminase3; TransglutaminaseE; TGM3_HUMAN.
Research Area	Neurobiology  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	25/76kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TGM3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium dependent. Transglutaminase 3 consists of two polypeptide chains activated from a single precursor protein by proteolysis. Transglutaminase 3 is involved the later stages of cell envelope formation in the epidermis and hair follicle. Subunit: Consists of two polypeptide chains, which are synthesized as a precursor form of a single polypeptide. Similarity: Belongs to the transglutaminase superfamily. Transglutaminase family. Database links: Entrez Gene: 7053 Human Entrez Gene: 21818 Mouse Omim: 600238 Human SwissProt: Q08188 Human SwissProt: Q08189 Mouse Unigene: 2022 Human Unigene: 2961 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. TGM3是转谷氨酰胺酶家族的主要成员之一，是一种钙离子依赖性蛋白酶，主要功能是参与角质化细胞的终末分化过程。

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