Product Name	Anti-VAMP1/AF594
Chinese Name	AF594标记的VAMP1囊泡相关膜蛋白1抗体
Alias	Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Vesicle-associated membrane protein 1.
Research Area	Tumour  immunology  Neurobiology  Signal transduction  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	13kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human VAMP-1 (79-118aa)
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Product Detail	background: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]. Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Subunit: Interacts with VAPA and VAPB. Subcellular Location: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Isoform 2: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein. Tissue Specificity: Nervous system, skeletal muscle and adipose tissue. Similarity: Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. Database links: Entrez Gene: 6843 Human Entrez Gene: 22317 Mouse Entrez Gene: 25624 Rat Omim: 185880 Human SwissProt: P23763 Human SwissProt: Q62442 Mouse SwissProt: Q63666 Rat Unigene: 20021 Human Unigene: 32321 Mouse Unigene: 31977 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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