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Product Name Anti-Japanese encephalitis virus E protein /AF350 Chinese Name AF350标记的猪乙脑病毒包膜蛋白抗体 Alias Japanese encephalitis virus,JEV E protein; Japanese encephalitis virus E protein; Japanese encephalitis virus envelope protein; JEV envelope protein. Research Area Bacteria and viruses Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 55kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Japanese Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes.
/organism="Japanese encephalitis virus"
/strain="JE/vaccine/China/Chengdu-Institute-of-Biological-Products-SA14-14-2"
Subcellular Location:
Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein.
Post-translational modifications:
Disulfide bond.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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