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Product Name GABARAPL1 Chinese Name γ氨基丁酸受体相关蛋白样1抗体 Alias APG8 like; APG8L; ATG8; ATG8L; Early estrogen regulated protein; GABA; GABA(A) receptor associated protein like 1; GABARAPL1; Gamma aminobutyric acid receptor associated protein like 1; GEC 1; GEC1; Glandular epithelial cell protein 1; GBRL1_HUMAN. Research Area Neurobiology Channel protein G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 14kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GABARAPL1: 41-117/117 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GABARAPL1 belongs to the MAP1 LC3 family. It increases cell surface expression of kappa type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.
Subunit:
Interacts with GABRG2 and beta-tubulin. Interacts with OPRK1.
Subcellular Location:
Cytoplasm, cytoskeleton. Membrane. Endoplasmic reticulum. Golgi apparatus.
Tissue Specificity:
Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine.
Similarity:
Belongs to the MAP1 LC3 family.
SWISS:
Q9H0R8
Gene ID:
23710
Database links:
Entrez Gene: 100135524 Guinea pig
Entrez Gene: 23710 Human
Entrez Gene: 57436 Mouse
Omim: 607420 Human
SwissProt: P60518 Guinea pig
SwissProt: Q9H0R8 Human
SwissProt: Q8R3R8 Mouse
Unigene: 524250 Human
Unigene: 14638 Mouse
Unigene: 118264 Rat
Product Picture Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GABARAPL1 Polyclonal Antibody, Unconjugated(SL8035R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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