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Product Name APOA4 Chinese Name 载LipoproteinA4抗体 Alias Apo AIV; APOA 4; Apolipoprotein A IV; MGC142154; MGC142156. literatures Specific References (1) | SL3876R has been referenced in 1 publications.[IF=5.008] Wang et al. Proteome-based identification of apolipoprotein A-IV as an early diagnostic biomarker in liver fibrosis. (2017) Oncotarge. 8:88951-88964 WB ; Rat.Research Area Cardiovascular immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, Rat, (predicted: Mouse, Dog, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 44kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human APOA4: 325-375/396 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties
Function:
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Subcellular Location:
Secreted.
Tissue Specificity:
Synthesized primarily in the intestine and secreted in plasma.
Post-translational modifications:
Phosphorylation sites are present in the extracellular medium.
Similarity:
Belongs to the apolipoprotein A1/A4/E family.
SWISS:
P06727
Gene ID:
337
Database links:Entrez Gene: 337 Human
Omim: 107690 Human
SwissProt: P06727 Human
Unigene: 1247 Human
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