Product Name	APOA4
Chinese Name	载LipoproteinA4抗体
Alias	Apo AIV; APOA 4; Apolipoprotein A IV; MGC142154; MGC142156.
literatures	Specific References  (1)     |     SL3876R has been referenced in 1 publications. [IF=5.008] Wang et al. Proteome-based identification of apolipoprotein A-IV as an early diagnostic biomarker in liver fibrosis. (2017) Oncotarge. 8:88951-88964  WB ;  Rat.   PubMed:29179490
Research Area	Cardiovascular  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Dog, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human APOA4: 325-375/396
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties Function: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Subcellular Location: Secreted. Tissue Specificity: Synthesized primarily in the intestine and secreted in plasma. Post-translational modifications: Phosphorylation sites are present in the extracellular medium. Similarity: Belongs to the apolipoprotein A1/A4/E family. SWISS: P06727 Gene ID: 337 Database links: Entrez Gene: 337 Human Omim: 107690 Human SwissProt: P06727 Human Unigene: 1247 Human
Product Picture	Sample: Brain (Rat) Lysate at 30 ug Kidney (Rat) Lysate at 30 ug Primary: Anti-APOA4 (SL3876R) at 1/200 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (SL0295G-HRP) at 1/3000 dilution Predicted band size: 42 kD Observed band size: 42 kD

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