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Rabbit Anti-5-HT antibody
Rabbit Anti-5-HT antibody
Serotonin; 5-hydroxytryptamine; 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride; 5 hydroxy tryptophan; 5 Hydroxytryptophan; 5HTP; 5-HT, 5-Hydroxytryptamine hydrochloride.5-羟色胺; 五羟色胺;
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  • NO.:SL1126R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name 5-HT
Chinese Name 5羟色胺抗体
Alias Serotonin; 5-hydroxytryptamine; 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride; 5 hydroxy tryptophan; 5 Hydroxytryptophan; 5HTP; 5-HT, 5-Hydroxytryptamine hydrochloride.  5-羟色胺; 五羟色胺;
literatures
Specific References  (6)     |     SL1126R has been referenced in 6 publications.
[IF=5.81] Shengyan Xi. et al. The Ciji-Hua’ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H22 Hepatocellular Carcinoma. Front Pharmacol. 2021; 12: 715824  IHC ;  Mouse.  
[IF=2.837] Arzu Hizay. et al. Lactobacillus acidophilus regulates abnormal serotonin availability in experimental ulcerative colitis. ANAEROBE. 2023 Apr;80:102710  IHC ;  Rat.  
[IF=2.43] Yin, Yue, et al. "Tong Xie Yao Fang relieves irritable bowel syndrome in rats via mechanisms involving regulation of 5-hydroxytryptamine and substance P."World Journal of Gastroenterology: WJG 21.15 (2015): 4536.  IHC-P ;  Rat.  
[IF=1.966] Tian L et al. Gingerol inhibits cisplatin-induced acute and delayed emesis in rats and minks by regulating the central and peripheral 5-HT, SP, and DA systems. J Nat Med. 2019 Nov 25.  IHC-P ;  rat&mink.  
[IF=1.918] Haili Zhang. et al. Morphological changes in the digestive tract of the Chinese soft-shelled turtle (Pelodiscus sinensis) during embryonic development. J HISTOTECHNOL. 2022 Aug 01  IHC ;  Chicken.  
[IF=0.392] Yildiz, M.. et al. The Effect of Chronic Intermittent Cold Exposure on Gastrin-, Somatostatin-, Secretin-, and Serotonin-Containing Cells in the Small Intestine of Rats. Biol Bull+. 2021 Dec;48(3):S95-S106  IHC ;  Rat.  
Product Type Small molecule anti 
Research Area Tumour  Cell biology  immunology  Neurobiology  Drugs and Compounds  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat, 
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 0.21268kDa
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated 5-HT 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.

Function:
Tryptophan is an amino acid occurring naturally in food. In the brain, it is converted to 5-hydroxy-tryptophan (5-HTP), which, in turn, is converted to serotonin. Serotonin is a neurotransmitter essential to regulating appetite, sleep, mood and pain levels.

SWISS:
N/A

CAS:
50-67-9

5-羟色胺在神经组织中有重要的功能,目前已肯定中枢神经系统有5-羟色胺能神经元。5-羟色胺可使大部分交感神经节前神经元兴奋,而使付交感节前神经元抑制。常用于消化道神经内分泌细胞及其Tumour的研究。5-羟色胺,又称血清素,由消化道EC细胞所分泌。
Product Picture
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-5-HT Polyclonal Antibody, Unconjugated(SL1126R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-5-HT Polyclonal Antibody, Unconjugated(SL1126R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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